Insulin and Diabetes, Obesity Hormones, from Muscle to Fat continue…
In Type Z diabetes, there is at first no shortage of insulin. In fact, early in the disease, there is more than usual. Yet, despite the insulin making its presence known in the muscle tissue, the muscle remains deaf to insulin’s messages, no matter how many are sent, and does nothing to stimulate the uptake of glucose or the storage of glycogen.
Another hormone which comes from the pancreas, in cells which live very near to those which make insulin, is glucagon. Whereas insulin is the hormone of plenty, glucagon is the hormone of scarcity: so when glucose is taken into the blood from the intestine during digestion of starchy foods, insulin is secreted and glucagon secretion is inhibited. During the night, when there is nothing left in your gut to absorb, glucagon secretion increases and insulin secretion is inhibited. (more…)